About the role
Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
The Opportunity
Praxis is seeking a field-based Medical Science Liaison (MSL) to support Medical Affairs activities for ulixacaltimide during prelaunch and potential launch. This role is focused on building trusted scientific partnerships, delivering high-quality scientific exchange, and generating actionable insights to inform medical strategy and ensure clinical readiness.
This is a field-facing, development-oriented role where you will engage healthcare professionals and investigators to communicate emerging clinical data, deepen disease state understanding, and identify unmet needs and potential barriers to patient care. You will work closely with cross-functional partners to ensure aligned and compliant execution of prelaunch and launch activities.
Success in this role requires strong scientific curiosity, effective communication skills, and the ability to operate with guidance while building confidence and independence in the field in a fast-paced environment.
Primary Responsibilities
Build and maintain scientific relationships with healthcare professionals, investigators, and key opinion leaders to support Medical Affairs objectives
Deliver accurate, balanced, and compliant scientific exchange on disease state, clinical data, and the ulixacaltimide profile
Support prelaunch medical readiness by educating stakeholders on emerging data, treatment paradigms, and patient identification considerations
Gather, synthesize, and communicate field insights (e.g., unmet needs, treatment patterns, clinical questions) to inform medical strategy
Identify and engage developing and established KOLs under the guidance of senior team members
Collaborate cross-functionally with internal partners to ensure aligned execution of field activities
Represent Praxis at scientific congresses and medical meetings, capturing and sharing relevant insights
Maintain up-to-date knowledge of CNS/neurology disease areas, clinical data, and competitive landscape
Ensure all activities are conducted in compliance with regulatory requirements, company policies, and industry standards
Qualifications and Key Success Factors
Advanced clinical or scientific degree (PharmD, PhD, MD, NP, PA, or RN)
Early to mid-career experience in medical affairs, clinical practice, clinical research, or related roles in biotech/pharma
Strong ability to learn and communicate scientific and clinical information clearly and credibly
Demonstrated ability to build professional relationships with healthcare providers
Interest in developing field-based expertise, including insight gathering and scientific engagement
Ability to manage multiple priorities with strong organization and attention to detail
Willingness to travel extensively (~60–80%)
Experience in neurology or CNS disorders preferred
Exposure to payer/market access concepts is a plus
Candidates with prior field-based experience and a demonstrated track record of independently driving site performance, influencing investigators, and improving trial execution may be considered at a higher level.
The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.
Compensation & Benefits
At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!
To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below.
These ranges reflect the base salary ranges the Company reasonably expects to pay for each level at the time of posting. Placement within the range will be based on job-related factors, including experience, qualifications, scope of responsibilities, and demonstrated track record of delivering results in similar roles.
Annualized Base Salary
$155,000—$175,000 USD
Company Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to
does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.
Originally posted on Himalayas