About the role
Clinical Trial Manager / SR Clinical Trial Manager - Remote - Brazil
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
Our Real World Solutions Team is looking for an experienced Clinical Trial Manager and Senior Clinical Trial Manager (CTM) that will be responsible for the end-to-end operational oversight of assigned clinical trials, ensuring delivery against agreed timelines, budget, and quality standards. This includes oversight of site management (remote and onsite), clinical team activities, and compliance with regulatory requirements.
The CTM leads Clinical Operations execution and serves as the primary point of accountability for trial delivery, working cross-functionally with internal teams and externally with sponsors.
What you are going to do:
Trial Execution & Oversight
Plan and manage all clinical operations activities across assigned trials.
Ensure delivery in line with scope, timelines, budget, and quality expectations.
Oversee site lifecycle activities, including start-up, activation, monitoring, and close-out.
Team Leadership & Oversight
Lead and oversee project specific operational activities of Clinical Research Associates (CRAs) and Site Management Associates (SMAs).
Provide direction, training, and study performance oversight for clinical team members.
Review monitoring reports, documentation, and study deliverables for quality and compliance.
Site & Monitoring Management
Develop and implement site management and monitoring plans.
Oversee remote and onsite monitoring activities, including visit planning and execution.
Ensure timely collection, review, and maintenance of trial documentation in CTMS.
Risk & Quality Management
Proactively identify risks and implement mitigation strategies.
Utilize metrics and dashboards to monitor study performance and quality.
Support data review and query management activities as needed.
Stakeholder Management
Collaborate with cross-functional teams (Project Management, Data Management, Finance).
Build and maintain strong relationships with sponsors and external partners.
Provide status updates, metrics, and key study insights to stakeholders.
Compliance & Governance
Ensure adherence to ICH-GCP, regulatory requirements, and internal SOPs.
Support audit and inspection readiness.
Additional Contributions
Participate in bid defense activities as required.
Contribute to process improvements and operational best practices.
What do you need:
Bachelor’s degree in life sciences or related field (or equivalent experience) with at least 1+ year of experience in a CTM or equivalent role (CRO or pharmaceutical environment)
Experience managing Phase III and/or IV clinical trials across multiple therapeutic areas.
Knowledge of risk-based monitoring (RBM) principles preferred
Experience managing North American studies
Ability to manage multiple studies and priorities in a fast-paced environment
Strong leadership, organizational, and problem-solving skills
Effective communication and stakeholder management skills
Willingness to travel (~15%)
Key Competencies
Leadership and team management
Strategic planning and execution
Risk assessment and mitigation
Decision-making and problem-solving
Cross-functional collaboration
Communication and stakeholder engagement
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
Originally posted on Himalayas