Lifelancer

Senior Principal Data Engineer

Remote, United States remote Entry $150,900 - $195,900
remote Technology & IT Salary listed Curated
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About the role

Job Title: Senior Principal Data Engineer
Job Location: Remote (US)
Job Location Type: Remote
Job Contract Type: Full-time
Job Seniority Level:
BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.
We are seeking a Senior Principal Data Engineer to serve as one of the highest-level technical leaders within the Data Engineering organization. Responsible for defining technical strategy, architecting enterprise-scale data platforms, and delivering scalable, secure, and high-quality data solutions.
This role combines deep expertise in cloud data platforms, software engineering, enterprise data architecture, data modeling, AI-assisted development, and technical governance. The successful candidate will influence technical direction across multiple business domains, establish engineering standards, and mentor engineers while remaining hands-on with architecture and solution design.
Key Responsibilities:
Enterprise Data Architecture

Design and evolve enterprise-scale data platform architecture supporting analytical, operational, and AI workloads.

Define reusable engineering frameworks, reference architectures, and technical standards.

Drive long-term platform strategy focused on scalability, security, performance, and maintainability.

Technical Leadership

Lead architecture reviews, technical design, and engineering governance for strategic initiatives.

Partner with engineering leadership to define technology roadmaps and drive engineering best practices.

Influence technical decisions across multiple teams without direct people management.

Data Engineering & Data Modeling

Design scalable ETL/ELT frameworks, enterprise data pipelines, and logical and physical data models.

Develop reusable, metadata-driven data integration frameworks.

Establish standards for data modeling, metadata management, lineage, and performance optimization.

AI-Driven Engineering

Champion AI-assisted software development across the engineering organization.

Evaluate and implement AI coding assistants and engineering productivity tools.

Build intelligent engineering accelerators, including:
AI-assisted code generation

Automated documentation

Code review assistance

Test generation

Data quality validation

AI-powered engineering copilots

Drive engineering productivity and innovation through Generative AI.

Cloud & Platform Engineering
Provide technical leadership across modern cloud technologies including:

Databricks

Azure

AWS

Docker

Kubernetes

Python

SQL

Git

REST APIs

CI/CD

Data Governance & Engineering Excellence

Design secure data platforms with enterprise governance, metadata, lineage, and RBAC/ABAC access controls.

Establish software engineering best practices including code quality, testing, automation, observability, and reusable components.

Mentorship & Collaboration

Mentor senior engineers and principal engineers while fostering engineering excellence.

Partner with Product Management, Data Science, Analytics, Data Governance, Enterprise Architecture, and Infrastructure teams to deliver strategic data capabilities.

Required Qualifications

Bachelor's degree in Computer Science, Engineering, Information Systems, or related field (Master's preferred).

7+ years of experience in Data Engineering, Software Engineering, or Data Platform Engineering.

Extensive experience designing enterprise-scale cloud data platforms and data architectures.

Strong expertise in conceptual, logical, and physical data modeling.

Expert-level programming skills in Python and SQL.

Hands-on experience with Databricks, Azure, AWS, Docker, Kubernetes, Git, REST APIs, and CI/CD.

Strong understanding of software architecture, design patterns, distributed systems, and secure data platform design.

Demonstrated ability to lead highly complex technical initiatives through influence rather than direct people management.

Excellent communication, stakeholder management, and technical leadership skills.

Preferred Qualifications

Experience in pharmaceutical, biotechnology, healthcare, or other regulated industries.

Experience with Databricks Unity Catalog, enterprise data governance, metadata management, and observability.

Experience with Infrastructure as Code (Terraform, Bicep, or similar).

Experience applying Generative AI to software and data engineering.

Leadership Expectations
The Senior Principal Data Engineer is expected to set technical direction, establish engineering standards, accelerate engineering productivity through automation and AI, mentor engineers, and serve as a trusted technical advisor to engineering and business leadership.
Success Metrics
Success will be measured by the scalability, reliability, and security of enterprise data platforms, delivery of strategic initiatives, adoption of reusable engineering frameworks, improvements in engineering productivity through AI, platform quality, and technical influence across the organization.
Global Competencies
When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

Fosters Teamwork

Provides and Solicits Honest and Actionable Feedback

Self-Awareness

Acts Inclusively

Demonstrates Initiative

Entrepreneurial Mindset

Continuous Learning

Embraces Change

Results-Oriented

Analytical Thinking/Data Analysis

Financial Excellence

Communicates with Clarity

Salary Range: $150,900.00 - $195,900.00 annuallyBeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.
We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact .

This job is curated by Lifelancer.
Lifelancer is a talent-hiring platform in Life Sciences, Pharma and IT. The platform connects talent with opportunities in pharma, biotech, health sciences, healthtech and IT domains.
Please apply via Lifelancer platform to get connected to the application page and to find similar roles.
Originally posted on Himalayas

Interview prep

Walk in with sharper answers.

Use this as a quick practice sheet before you speak with the employer.

Role
Technology & IT API integration Data Analysis MySQL Python Remote Collaboration remote

Likely questions

  1. Tell us about work you have done that is close to the Senior Principal Data Engineer role.
  2. How would you approach your first 30 days at Lifelancer?
  3. Which of API integration, Data Analysis and MySQL have you used recently, and what did it help you achieve?
  4. Describe a time you solved a problem without waiting to be told exactly what to do.
  5. How do you stay organised and communicate clearly when working remotely?

Prepare before the call

  • A recent example that proves your experience with API integration, Data Analysis and MySQL.
  • One short story with a problem, your action, and the result.
  • Two examples that show the strengths listed on your CV.
  • A clear reason why this role and company interest you.
  • Your availability, preferred work style, and salary expectations.

Ask them

  • What would success look like in the first 90 days?
  • What are the main problems this hire should help solve?
  • How does the team give feedback and measure good work?
  • What does a normal working week look like for this role?
Practice line

I am interested in the Senior Principal Data Engineer role because I can bring practical experience in API integration, Data Analysis and MySQL, learn the team quickly, and contribute to the outcomes Lifelancer needs from this hire.

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