Sanford Health

Principal AI Architect

United States full-time Executive $53 - $88
full-time Executive level Technology & IT Salary listed Curated
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About the role

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Work Shift:
8 Hours - Day Shifts (United States of America)Scheduled Weekly Hours:
40Compensation:
Salary Range: $53.00 - $87.50Pay starts at $53 and increases according to yeas of applicable experience.Union Position:
NoDepartment Details
Don't miss this opportunity to join talented team of architects as we build new enterprise AI products and functions. Experience a great work environment and enjoy the satisfaction of helping deliver our healthcare mission.Summary
The Principal AI Architect is responsible for designing, governing, and implementing enterprise AI/ML solutions that improve clinical outcomes, operational efficiency, workforce productivity, and business performance across Sanford. Serves as a technical leader, partnering with business stakeholders, clinical leaders, data teams, and technology teams to translate business challenges into scalable, secure, and compliant AI-enabled solutions.

The Principal AI Architect defines architecture standards, evaluates emerging AI technologies, and ensures solutions align with organizational goals, healthcare regulations, security requirements, and responsible AI principles. Combines expertise in AI, cloud architecture, data platforms, healthcare interoperability, and enterprise integration.Job Description
The Principal AI Architect designs and implements enterprise AI architectures supporting: Generative AI, Machine Learning, Conversational AI, Intelligent Automation, Predictive Analytics, and Clinical Decision Support. Develops architecture patterns, standards, and reference designs for AI solutions. Creates scalable, resilient, and secure AI platforms across cloud and hybrid environments. Defines integration approaches connecting AI systems with enterprise applications and data platforms.Designs AI solutions that leverage healthcare data while maintaining privacy and security requirements. Architects integrations with healthcare and business systems such as EHR, ERP, HR, and collaboration platforms. Supports implementation of healthcare interoperability standards including HL7, FHIR, CDA, DICOM, and X12. Collaborates with data architects and engineers to establish AI-ready data pipelines and governance frameworks.Ensures AI solutions comply with HIPAA, HITECH, organizational security standards, and healthcare regulatory requirements. Establishes controls for model governance, monitoring, auditability, and responsible AI practices. Conducts architecture reviews and risk assessments for AI initiatives. Partners with cybersecurity, compliance, and privacy teams to mitigate AI-related risks.Evaluates emerging AI technologies, vendors, platforms, and frameworks. Develops recommendations regarding build-versus-buy decisions. Leads proof-of-concept and pilot initiatives for new AI capabilities. Stays current with healthcare AI trends and industry best practices.Partners with clinical, operational, and business leaders to identify AI opportunities. Translates complex technical concepts into business-friendly recommendations. Provides architectural guidance to engineers, developers, and data scientists. Participates in architecture governance and strategic planning activities. Contributes to AI education, adoption, and change management efforts across the organization.Qualifications
Bachelor’s degree in Computer Science, Information Technology, Engineering or a related technical field required. Master’s degree is preferred.

7 years of experience in solution architecture, application architecture, data architecture, or software engineering. 3 years of experience designing AI, machine learning, analytics, or automation solutions. Experience with cloud platforms such as Microsoft Azure, AWS, or Google Cloud. Experience designing enterprise integrations using APIs, event-driven architecture, or middleware platforms. Experience working with complex enterprise systems and data environments.

AI and Cloud architecture certifications preferred.Sanford is an EEO/AA Employer M/F/Disability/Vet.
If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-949-5678 or send an email to .
Originally posted on Himalayas

Interview prep

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Executive
Technology & IT API integration Data Analysis Human Resources Principal Architect Executive level

Likely questions

  1. Tell us about work you have done that is close to the Principal AI Architect role.
  2. How would you approach your first 30 days at Sanford Health?
  3. Which of API integration, Data Analysis and Human Resources have you used recently, and what did it help you achieve?
  4. How have you led people, improved a process, or made a hard decision in a previous role?
  5. How do you handle busy days, changing priorities, or pressure at work?

Prepare before the call

  • A recent example that proves your experience with API integration, Data Analysis and Human Resources.
  • One short story with a problem, your action, and the result.
  • Two examples that show the strengths listed on your CV.
  • A clear reason why this role and company interest you.
  • Your availability, preferred work style, and salary expectations.

Ask them

  • What would success look like in the first 90 days?
  • What are the main problems this hire should help solve?
  • How does the team give feedback and measure good work?
  • What does a normal working week look like for this role?
Practice line

I am interested in the Principal AI Architect role because I can bring practical experience in API integration, Data Analysis and Human Resources, learn the team quickly, and contribute to the outcomes Sanford Health needs from this hire.

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