About the role
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Let's do something amazing together! The Associate Director, National Accounts will play a critical role in enabling patient access to Arrowhead's first commercial asset, Redemplo (plozasiran, siRNA targeting APOC3), as well as an expanding pipeline of innovative therapies across multiple therapeutic areas. This product has demonstrated compelling clinical data to date and received approval in November 2025 for the treatment of Familial Chylomicronemia Syndrome (FCS). Redemplo (plozasiran) remains in late-stage development for the treatment of Severe Hypertriglyceridemia (SHTG), with approval anticipated in Q2 2027.
This individual will own a dedicated portfolio of payer and PBM accounts while also serving as a strategic, customer-facing partner to the National Account Directors (NADs) on Arrowhead's broader national accounts, and as a centralized source of truth for payer contracts, formulary coverage, payer policies, and utilization management criteria across Arrowhead's U.S. Market Access footprint. The role will translate formulary, claims, and specialty pharmacy data into payer strategy and field-facing insights, partnering closely with the NADs, Trade, Distribution, and Patient Services leadership to strengthen Arrowhead's payer intelligence capabilities and represent that intelligence directly to internal leadership and external payer and PBM audiences. This is an individual contributor role with no direct reports, requiring high executive presence, polished presentation skills, and the confidence to stand alongside the NADs in front of senior payer and PBM stakeholders.
This is a field-based or remote role that requires periodic travel to Arrowhead's Corporate Headquarters in Pasadena, CA, and to payer and PBM industry conferences, as business needs dictate
Responsibilities
Own and manage a dedicated portfolio of payer and PBM accounts, serving as the primary point of contact for day-to-day payer engagement, relationship management, and issue resolution
Support National Account Directors (NADs) on payer and PBM engagements as needed, bringing data-driven insights to the account team
Represent Arrowhead directly with payer and PBM leadership, presenting formulary, policy, and performance insights at business reviews, national conferences, and sales meetings
Attend payer and PBM industry conferences alongside NADs and cross-functional leadership to represent Arrowhead's payer intelligence capabilities and gather market intelligence
Serve as the centralized source of truth for payer formulary coverage, published payer policies, and utilization management (UM) criteria, including prior authorization, step therapy, and quantity limit requirements, across Commercial, Medicare Part D, and Medicaid books of business
Monitor and analyze formularies and policy databases to track payer coverage decisions, formulary tier placement, and UM criteria across assigned payer and PBM accounts
Analyze pharmacy claims data to identify prior authorization trends, claims patterns, approval and denial rates that signal emerging access barriers
Coordinate with Trade, Distribution, and Patient Services to analyze HUB and specialty pharmacy patient-journey data, translating claims and PA insights into access trends
Develop and deliver regular communications to the field on payer coverage wins, policy changes, and key analytical insights to support account and sales team pull-through
Collaborate cross-functionally with Market Access, Trade, Distribution, Patient Services, Sales, Commercial Analytics, and Finance to address payer access challenges
Ensure full compliance with US healthcare regulations, legal standards, and corporate policies in all analyses and communications
Requirements
Bachelor's Degree
7 years of pharmaceutical, biotech, PBM, payer, or GPO experience, with a strong background in market access analytics, payer policy, or managed markets
Demonstrated ability to translate complex data into clear, actionable insights that inform payer strategy and communications
Ability to build credibility and influence cross-functionally without direct authority in a highly matrixed environment
Self-motivated and collaborative, able to operate with strategic independence
High executive presence and polished presentation skills, with the ability to present confidently to internal senior leadership and external payer and PBM audiences
Willingness and ability to travel approximately 25% for payer and PBM meetings, industry conferences, and periodic visits to Arrowhead’s corporate headquarters in Pasadena, California.
Preferred
Strong understanding of the Commercial, Medicare Part D, and Medicaid managed care books of business
Highly analytical, with experience working across formulary and policy data (e.g., MMIT), pharmacy claims, HUB and specialty pharmacy data, and payer performance reporting
Experience supporting or partnering with National Account Directors or Key Account Managers on payer engagement and negotiations highly desired
Master’s / Advanced Degree (MBA, MPH, PharmD)
California pay range
$180,000—$220,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
California Applicant Privacy Policy
Originally posted on Himalayas